Bilbao is a municipality and city in Spain, a major city in the province of Biscay in the autonomous community of the Basque Country. It is the main urban area in what is defined as the Greater Basque region. Situated in the north-central part of Spain, its main urban core is surrounded by two small mountain ranges. After its foundation in the early 14th century by Diego López V de Haro, head of the powerful Haro family, the city was a commercial hub of the Basque Country that enjoyed significant importance in Green Spain. This was due to its port activity based on the export of iron extracted from the Biscayan quarries. Throughout the nineteenth century and the beginning of the twentieth, Bilbao experienced heavy industrialisation, making it the centre of the second-most industrialised region of Spain. Today, Bilbao is a vigorous service city that is experiencing an ongoing social, economic, and aesthetic revitalisation process, started by the iconic Bilbao Guggenheim Museum, and continued by infrastructure investments, such as the airport terminal, the rapid transit system, the tram line, the Alhóndiga, and the currently under development Abandoibarra and Zorrozaurre renewal projects. Bilbao is also home to football club Athletic Club de Bilbao, a significant symbol for Basque nationalism due to its promotion of Basque players and one of the most successful clubs in Spanish football history.

Seville is the artistic, cultural, and financial capital of southern Spain. It is the capital of the autonomous community of Andalusia and of the province of Seville. It is situated on the plain of the River Guadalquivir, with an average elevation of 7 metres (23 ft) above sea level. The inhabitants of the city are known as sevillanos (feminine form: sevillanas) or hispalenses, following the Roman name of the city, Hispalis. The tapas scene is one of the main cultural attractions of the city: people go from one bar to another, enjoying small dishes called tapas (literally "lids" or "covers" in Spanish, referring to their probable origin as snacks served on small plates used to cover drinks). Local specialities include fried and grilled seafood (including squid, choco (cuttlefish), swordfish, marinated dogfish, and ortiguillas), grilled and stewed meat, spinach with chickpeas, Jamón ibérico, lamb kidneys in sherry sauce, snails, caldo de puchero, and gazpacho. A sandwich known as a serranito is the typical and popular version of fast food.

The capital of Portugal, Lisbon (Portuguese: Lisboa) has experienced a renaissance in recent years, with a contemporary culture that is alive and thriving and making its mark in today's Europe. Perched on the edge of the Atlantic Ocean, Lisbon is one of the rare Western European cities that faces the ocean and uses water as an element that defines the city. Lisbon enchants travellers with its white-bleached limestone buildings, intimate alleyways, and an easy-going charm that makes it a popular year-round destination.

Bordeaux is a port city on the Garonne River in southwest France, with an estimated (2008) population of 250,082. The Bordeaux-Arcachon-Libourne metropolitan area, has a population of 1,010,000 and constitutes the sixth-largest urban area in France. It is the capital of the Aquitaine region, as well as the prefecture of the Gironde department. Its inhabitants are called Bordelais. Bordeaux is the world's major wine industry capital. It is home to the world's main wine fair, Vinexpo, while the wine economy in the metro area moves 14.5 billion euros each year. Bordeaux wine has been produced in the region since the eighth century. The historic part of the city is on the UNESCO World Heritage List as "an outstanding urban and architectural ensemble" of the 18th century.

Porto (also known as Oporto in English), is the second largest city in Portugal after Lisbon and one of the major urban areas of the Iberian Peninsula. The urban area of Porto, which extends beyond the administrative limits of the city, has a population of 1.4 million (2011) in an area of 389 km2 (150 sq mi), making it the second-largest urban area in Portugal. Located along the Douro river estuary in Northern Portugal, Porto is one of the oldest European centres, and its historical core was proclaimed a World Heritage Site by UNESCO in 1996. The western part of its urban area extends to the coastline of the Atlantic Ocean. Its settlement dates back many centuries, when it was an outpost of the Roman Empire. One of Portugal's internationally famous exports, port wine, is named for Porto, since the metropolitan area, and in particular the caves of Vila Nova de Gaia, were responsible for the packaging, transport and export of the fortified wine. In 2014, Porto was elected The Best European Destination by the Best European Destinations Agency.

Barcelona – Spain's enchanting capital, second largest and most populous city. It is a huge city that vibrates with life, and there’s certainly not another city in the country to touch it for its sheer style, looks or energy. It is one of the world's leading tourist, economic, trade fair and cultural centers, and its influence in commerce, education, entertainment, media, fashion, science, and the arts all contribute to its status as one of the world's major global cities. Barcelona is home to masterpieces of many great architects – the most famous of which is Antoni Gaudí.