Seville is the artistic, cultural, and financial capital of southern Spain. It is the capital of the autonomous community of Andalusia and of the province of Seville. It is situated on the plain of the River Guadalquivir, with an average elevation of 7 metres (23 ft) above sea level. The inhabitants of the city are known as sevillanos (feminine form: sevillanas) or hispalenses, following the Roman name of the city, Hispalis. The tapas scene is one of the main cultural attractions of the city: people go from one bar to another, enjoying small dishes called tapas (literally "lids" or "covers" in Spanish, referring to their probable origin as snacks served on small plates used to cover drinks). Local specialities include fried and grilled seafood (including squid, choco (cuttlefish), swordfish, marinated dogfish, and ortiguillas), grilled and stewed meat, spinach with chickpeas, Jamón ibérico, lamb kidneys in sherry sauce, snails, caldo de puchero, and gazpacho. A sandwich known as a serranito is the typical and popular version of fast food.

Barcelona – Spain's enchanting capital, second largest and most populous city. It is a huge city that vibrates with life, and there’s certainly not another city in the country to touch it for its sheer style, looks or energy. It is one of the world's leading tourist, economic, trade fair and cultural centers, and its influence in commerce, education, entertainment, media, fashion, science, and the arts all contribute to its status as one of the world's major global cities. Barcelona is home to masterpieces of many great architects – the most famous of which is Antoni Gaudí. 

Valencia is the most populous city of the Autonomous Community of Valencia and the third largest city in Spain, with a population of 809,267 in 2010. It is the 15th-most populous municipality in the European Union. It is integrated into an industrial area on the Costa del Azahar. Its historic centre is one of the largest in Spain, with approximately 169 hectares; this heritage of ancient monuments, views and cultural attractions makes Valencia one of the country's most popular tourist destinations!

Cartagena is a Spanish city and a majornaval station located in the Region of Murcia, by the Mediterranean coast, south-eastern Spain. The metropolitan area of Cartagena, known as Campo de Cartagena, has a population of 409,586 inhabitants. Cartagena has been inhabited for over two millennia, being founded around 227 BC by the Carthaginian Hasdrubal the Fair as Qart Hadasht, the same name as the original city of Carthage. Much of the historical weight of Cartagena in the past goes to its coveted defensive port, one of the most important in the western Mediterranean. As far back as the 16th century it was one of the most important naval ports in Spain, together with Ferrol in the North. It is still an important naval seaport, the main military haven of Spain, and is home to a large naval shipyard. The confluence of civilizations as well as its strategic harbour, together with the rise of the local mining industry is manifested by a unique artistic heritage, with a number of landmarks such as the Roman Theatre, the second largest of the Iberian Peninsulaafter the one in Mérida, an abundance of Phoenician, Roman, Byzantine and Moorish remains, and a plethora of Art Nouveaubuildings, a result of the bourgeoisie from the early 20th century. Cartagena is now established as a major cruise ship destination in the Mediterranean and an emerging cultural focus. It is the first of a number of cities that eventually have been named Cartagena, most notably Cartagena de Indias (Cartagena of the Indies) in Colombia.

Civitavecchia is a town and comune of the Metropolitan City of Rome in the central Italian region of Lazio. A sea port on the Tyrrhenian Sea, the name ''Civitavecchia'' means "ancient town". The modern city was built over a pre-existing Etruscan settlement. The massive Forte Michelangelo was first commissioned from Donato Bramante by Pope Julius II, to defend the port of Rome. The upper part of the "maschio" tower, however, was designed by Michelangelo, whose name is generally applied to the fortress. North of the city at Ficoncella are the Terme Taurine baths frequented by Romans and still popular with the Civitavecchiesi. The modern name stems from the common fig plants among the various pools. And also next to the town is the location of the cruise ship docks. All major cruise lines start and end their cruises at this location, and others stop for shore excursion days that allow guests to see Rome and Vatican sights, which are ninety minutes away.